Search
Lab Questions? Call 617-724-LABS • Full List of TestsAdvanced Search

 
Lung biopsy
 
Test Synonyms:
Lung biopsy
 
Lab:
Anatomic Pathology
Inpatient Req:
Pathology (#10016)  
Outpatient Req:
Pathology (#10016)  
Specimen:
Result Time:
3 days for routine studies  
Reference Interval:
 
Important Information:
Open lung biopsies should be cultured under sterile conditions in the surgical suite. The specimen for histopathology should consist of at least two cubic centimeters of untraumatized tissue. It should include relatively normal lung as well as abnormal tissue. A biopsy specimen which includes only end-stage pulmonary fibrosis will not provide a specific diagnosis. The tips of the right middle lobe and lingula may not be representative of the remainder of the lung and should be avoided if possible, or the specimen should include two cubic centimeters in addition to the tip. An open lung biopsy specimen should not be allowed to collapse. This can be accomplished either by placing it in formalin in the operating room immediately after excision or by sending it to Pathology with clamps still attached. If frozen section diagnosis is required, the latter procedure is necessary. Percutaneous aspiration for cytology is handled as a cytologic specimen. Transbronchial and percutaneous needle biopsies should be placed in formalin. Smears for Pneumocystis, lipid or hemosiderin should be left to dry in the air and submitted for staining. When there is a question of lymphoma, interstitial pneumonitis, pulmonary hemorrhage, or collagen vascular disease, a portion of the specimen should be frozen and sent to the Immunopathology Laboratory. When there is a question of small cell carcinoma, benign tumor, sarcoma or mesothelioma, a piece of tissue should be placed in glutaraldehyde for possible electron microscopy. Excision of an arteriovenous malformation should be delivered unfixed for study by vascular injection. Excision of hyperlucent lung and congenital abnormalities should not be incised but delivered unfixed for study by vascular injection. Excision of hyperlucent lung and congenital abnormalities should not be incised but delivered whole to pathology and arrangements made for morphometrics. Biopsy specimens with a question of lipoid pneumonia should be placed in absolute alcohol. Please call Dr. Eugene Mark (x6-8891) with any questions about lung biopsies.

Last Reviewed on 4/10/2005