From: Elizabeth M. Van Cott, M.D., and Michael Laposata, M.D., Ph.D., "Coagulation." In: Jacobs DS et al, ed. The Laboratory Test Handbook, 5th Edition. Lexi-Comp, Cleveland, 2001; 327-358.
Index of Tests
Factor V Leiden [CO006300]
Abstract See Activated
Protein C Resistance and Factor V Leiden Mutation. The term
"factor V Leiden" is often used interchangeably with activated protein
C resistance, although they are not true synonyms. The factor V
Leiden mutation causes the vast majority of cases of activated protein
C resistance. Whether or not additional mutations other than factor
V Leiden can cause clinically-significant activated protein C resistance
is under continued investigation.